Breaking
● GLP-1 trial shows 34% reduction in cardiovascular events over 5 years ● Senolytics drug enters Phase III — first human trial results expected Q1 2027 ● FDA fast-tracks CRISPR base-editing therapy for sickle cell disease ● Longevity biotech index up 12% YTD as institutional capital accelerates ● AI diagnostic platform achieves 97.2% accuracy in early-stage pancreatic cancer detection ● Harvard study links CGM use to 23% lower all-cause mortality in non-diabetics
Impact Health Magazine
Biotech founders disrupting medicine
Leadership & Culture
The Disruptors

Founders Rewriting the Rules of Medicine

They left Wall Street, Silicon Valley, and the world's top research labs to build companies that could add decades to human life. These are their stories.

"The most dangerous person in healthcare is not a regulator or a competitor. It is a founder who has personally experienced the system's failure."
Vinod Khosla, Khosla Ventures
$28B

Raised by longevity-focused startups in 2025

340+

Longevity biotech companies founded since 2020

7

Longevity unicorns created in the past 24 months

Profiles

The Founders Changing Medicine

Dr. Nir Barzilai

Dr. Nir Barzilai

Targeting Aging with Metformin (TAME)

Director, Institute for Aging Research, Albert Einstein College of Medicine

The first FDA-approved clinical trial targeting aging itself — not a disease, but the biological process that causes all disease.

Laura Deming

Laura Deming

Longevity Fund

Founder & General Partner

The world's first venture fund dedicated exclusively to longevity science, backing companies that target the hallmarks of aging at the molecular level.

Dr. George Church

Dr. George Church

Rejuvenate Bio

Professor of Genetics, Harvard Medical School

Using gene therapy to reverse multiple hallmarks of aging simultaneously — the most ambitious anti-aging program in the history of science.

Mehmood Khan

Mehmood Khan

Hevolution Foundation

CEO

Deploying $1 billion annually to fund the most promising aging research globally — the largest philanthropic commitment to longevity science ever made.